What happens to enzyme activity as temperature rises beyond the optimal temperature?

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Multiple Choice

What happens to enzyme activity as temperature rises beyond the optimal temperature?

Explanation:
Enzyme activity increases with temperature as molecules move faster and collide more often, but beyond the optimum temperature that heat destabilizes the enzyme’s folded shape. The weak bonds that hold the protein together break or weaken, causing denaturation. When the enzyme unfolds or its active site is distorted, substrates can’t bind properly or the catalytic residues misalign, so the reaction rate drops quickly. In many cases this loss of structure is irreversible, leading to a substantial decrease in activity at temperatures above the optimum.

Enzyme activity increases with temperature as molecules move faster and collide more often, but beyond the optimum temperature that heat destabilizes the enzyme’s folded shape. The weak bonds that hold the protein together break or weaken, causing denaturation. When the enzyme unfolds or its active site is distorted, substrates can’t bind properly or the catalytic residues misalign, so the reaction rate drops quickly. In many cases this loss of structure is irreversible, leading to a substantial decrease in activity at temperatures above the optimum.

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